(S,R,S)-AHPC-Boc derivative 1, CAS [[2086298-33-9]] Preis auf Anfrage

Product Overview

• Article Name: (S,R,S)-AHPC-Boc derivative 1, CAS [[2086298-33-9]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T206790
• Supplier Catalog Number: T206790
• Alternative Catalog Number: TGM-T206790-10MG, TGM-T206790-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: VH032-Boc derivative 1

Product Description

(S,R,S)-AHPC-Boc derivative 1 (Compound 80-9, VH032-Boc derivative 1) is a selective proteasomal degrader targeting MALT1, which recruits the E3 ubiquitin ligase CRBN to form a ternary complex with MALT1. This interaction leads to the ubiquitination and subsequent proteasomal degradation of MALT1. By disrupting the CBM complex, (S,R,S)-AHPC-Boc derivative 1 inhibits the NF-kappaB signaling pathway and shows potential in inducing apoptosis in ABC-DLBCL cells. It holds promise for research into MALT1-dependent cancers, such as diffuse large B-cell lymphoma (DLBCL).

Product Properties

• Molecular Weight: 560.705
• CAS Number: [2086298-33-9]
• Formula: C28H40N4O6S
• Target: MALT

Images

T206790