Antiproliferative agent-67 (Compound 5g) is a PI3K inhibitor with a selectivity index (SI) of 7.72 against breast cancer cells (MCF-7). It exhibits antiproliferative activity against MCF-7 cells by inhibiting PI3K protein activity through hydrogen bonding and intermolecular hydrophobic interactions, making it useful for breast cancer research.
Target:
PI3K
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