AX-53802 is a ferroptosis (ferroptosis) inducer targeting GPX4, with an IC50 of 0.34 µM. It forms a covalent bond with GPX4, initiating membrane translocation upon binding. In combination with FAK/Src inhibitors, AX-53802 enhances cell death. This compound is applicable in cancer research.
Molecular Weight:
408.422
CAS Number:
[1008482-71-0]
Formula:
C23H21FN2O4
Target:
Ferroptosis|||Glutathione Peroxidase
T206898
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