L1BC8 (compound 13a) is a BRD4 PROTAC degrader with anticancer properties. It also serves as a drug-linker conjugate for ADC, suitable for ADC synthesis. The resulting BRD4 degrader antibody conjugates demonstrate potent antigen-dependent BRD4 degradation and antiproliferative activity in cellular assays.
Molecular Weight:
1745.92
CAS Number:
[2417370-68-2]
Formula:
C86H98F2N16O18S2
Target:
Epigenetic Reader Domain|||Drug-Linker Conjugates for ADC|||PROTACs
T206916
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