TH287 is a selective MTH1 inhibitor(IC50 : 0.8 nM). It causees incorporation of oxidized dNTPs in cancer cells, leading to DNA damage, cytotoxicity and therapeutic responses in patient-derived mouse xenografts.
Molecular Weight:
305.59
Purity:
99.50%
CAS Number:
[1638211-05-8]
Formula:
C11H11Cl3N4
Target:
MTH1|||DNA/RNA Synthesis
T2069L
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