HEMTAC WEE1 degrader-1, CAS [[3002417-64-0]] Preis auf Anfrage

Product Overview

• Article Name: HEMTAC WEE1 degrader-1, CAS [[3002417-64-0]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T207012
• Supplier Catalog Number: T207012
• Alternative Catalog Number: TGM-T207012-10MG,TGM-T207012-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

HEMTACWEE1degrader-1 is a WEE1-targeting heterobifunctional chimeric degrader (HEMTAC) facilitated by HSP90, exhibiting an HSP90 enzyme inhibitory activity with an IC50 of 16.76 nM. It enhances the ubiquitination and subsequent degradation of WEE1, effectively blocking the G2/M cell cycle transition. This compound shows anticancer properties in patient-derived xenograft (PDX) models of acute myeloid leukemia (AML). HEMTACWEE1degrader-1 is utilized in AML research.

Product Properties

• Molecular Weight: 1062.27
• CAS Number: [3002417-64-0]
• Formula: C57H71N15O6
• Target: HSP|||Wee1

Images

T207012