EGFR-IN-87 (Compound Example 2) hydrochloride is an EGFR tyrosine kinase inhibitor. It has IC50 values of 3.1 nM, 1.3 nM, and 7.1 nM for EGFR_d746-750, EGFR_L858R/T790, and EGFR_WT, respectively, in A431 cells. EGFR-IN-87 hydrochloride is useful for cancer research.
Formula:
C28H34ClN7O2
Target:
EGFR
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