RIPK1-IN-30 (compound 24) is a potent RIPK1 inhibitor with an IC50 of 2.01 µM. It demonstrates a protective effect in the HT-29 cell model of TSZ-induced necroptosis, with an EC50 of 6.77 µM.
Formula:
C27H25FN2O4
Target:
RIP kinase
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