HBV-IN-52 is a selective inhibitor of HBV and a derivative of Neplanocin A, displaying significant anti-hepatitis B virus replication activity with an EC50 of 0.96 µM. It also suppresses the secretion of hepatitis B surface antigen (HBsAg) with an EC50 of 0.82 µM. HBV-IN-52 is useful for studying chronic hepatitis B (CHB) infection.
Formula:
C12H13IN4O3
Target:
HBV
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