CDK9/HDAC1/HDAC3-IN-1, CAS [[2197029-81-3]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T207433
Supplier Catalog Number:
T207433
Alternative Catalog Number:
TGM-T207433-10MG,TGM-T207433-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
CDK9/HDAC1/HDAC3-IN-1 is a dual inhibitor targeting CDK9 and HDAC enzymes. It potently suppresses the activity of CDK9, HDAC1, and HDAC3, with IC50 values of 0.17 µM, 1.73 µM, and 1.11 µM, respectively. The compound inhibits cancer cell growth by inducing apoptosis and causing cell cycle arrest at the G2/M phase. In a mouse model using TNBC MDA-MB-231 xenografts, it effectively hinders tumor progression. This compound exhibits broad-spectrum anticancer effects, notably against breast cancer, cervical cancer, and liver cancer.
Molecular Weight:
470.55
CAS Number:
[2197029-81-3]
Formula:
C24H22N8OS
Target:
Apoptosis|||CDK|||HDAC
T207433
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