TNKS-IN-3 (Compound 6) is a TNKS2 inhibitor with a Ki of 8.5 nM. It demonstrates strong activity with an IC50 of 71 nM, effectively inhibiting the WNT/beta-catenin signaling pathway, and is useful for research in cancer and fibrosis.
Formula:
C30H27N5O4S
Target:
PARP
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