SHP2-IN-37 (compound C5) is a potent allosteric inhibitor selective for SHP2, with an IC50 of 0.023 µM. It exhibits antiproliferative effects on KYSE-520 and MV-411 cells, with IC50 values of 6.97 µM and 0.67 µM, respectively.
Formula:
C19H22Cl2N4O2S
Target:
Phosphatase
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