TRPC6 antagonist-1 (X26) is a TRPC6 inhibitor with IC50 values of 0.97 µM for TRPC6, 3.93 µM for TRPC3, 5.77 µM for TRPC5, and 4.37 µM for TRPC7. Additionally, TRPC6 antagonist-1 hinders TGF-beta1-induced myofibroblast differentiation, thereby mitigating renal fibrosis.
Formula:
C26H32N4O2S
Target:
TRP/TRPV Channel
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