T0080 is an FPR-1 antagonist. It reduces apoptosis (Apoptosis) and inhibits the production of reactive oxygen species (ROS) and pro-inflammatory cytokines (TNF-alpha and IL-1beta) in plaque macrophages within ApoE-/- mouse models, thereby slowing the progression of atherosclerosis.
Molecular Weight:
457.45
CAS Number:
[2785323-68-2]
Formula:
C24H22F3N3O3
Target:
Interleukin|||Reactive Oxygen Species|||Apoptosis
T207682
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