Fluoxetine-Conjugated Platinum(IV) prodrug-1 Preis auf Anfrage
Biozol Catalog Number:
TGM-T207715
Supplier Catalog Number:
T207715
Alternative Catalog Number:
TGM-T207715-10MG,TGM-T207715-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Fluoxetine-Conjugated Platinum(IV) prodrug-1 is an eEF2K inhibitor that can hinder the proliferation of cancer cells, induce DNA damage, and cause cell cycle arrest at the S phase, leading to apoptosis (Apoptosis). It also promotes the accumulation of reactive oxygen species (ROS) and disrupts mitochondrial function. This prodrug inhibits the migration and invasion of TNBC cells by suppressing MMP-2 activity and induces autophagy in TNBC cells through AMPK activation. In the 4T1-Luc mouse model, it exhibits antitumor activity and triggers immune suppression. Fluoxetine-Conjugated Platinum(IV) prodrug-1 is relevant for research in triple-negative breast cancer (TNBC).
Formula:
C21H28Cl2F3N3O5Pt
Target:
Autophagy|||AMPK|||MMP|||Apoptosis|||CaMK
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