LXG6403 is a powerful dual-thiazole LOX cell activity inhibitor with an IC50 of 1.3 µM. It exhibits anticancer properties by restructuring the extracellular matrix, enhancing the penetration of chemotherapeutic drugs, inducing reactive oxygen species (ROS) production, and promoting cell death mediated by DNA damage, thereby overcoming chemotherapy resistance in triple-negative breast cancer.
Molecular Weight:
345.44
CAS Number:
[315705-04-5]
Formula:
C15H15N5OS2
Target:
ROS|||Others|||Apoptosis|||Lipoxygenase|||FAK
T207776
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