Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, CUDC-907 inhibits the activity of both PI3K class I isoforms and HDAC, thereby preventing the activation of the PI3K-AKT-mTOR signal transduction pathway that is often overactivated in many cancer cell types.
Molecular Weight:
508.55
Purity:
99.87%
CAS Number:
[1339928-25-4]
Formula:
C23H24N8O4S
Target:
HDAC|||PI3K|||Apoptosis
T2078
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