Tryptophan-cholic acid (Trp-CA) is a microbial amino acid-binding bile acid (MABA), serving as an endogenous ligand and agonist for MRGPRE (Mas-related GPCR family member E), thereby inducing GLP-1 secretion. Tryptophan-cholic acid improves glucose tolerance in diabetic mice and may be utilised for studies on type 2 diabetes.
Molecular Weight:
594.78
Purity:
100.00%
CAS Number:
[1630745-39-9]
Formula:
C35H50N2O6
Target:
GPCR|||Endogenous Metabolite
T207803
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