Antitumor agent-123 (Compound 4d) effectively inhibits various kinase targets with anticancer properties, including JAK2, JAK3, HDAC1, and HDAC6, with IC50 values of 34.6 µM for JAK2 and 2.6 µM for JAK3. In solid tumor models, Antitumor agent-123 demonstrates moderate activity.
Formula:
C19H14ClFN6O2
Target:
HDAC|||JAK
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