HR488B is a potent inhibitor of HDAC1. It specifically hinders the growth of CRC cells by inducing cell cycle arrest at the G0/G1 phase and promoting apoptosis. Furthermore, HR488B leads to mitochondrial dysfunction, the production of reactive oxygen species (ROS), and the accumulation of DNA damage.
Formula:
C24H26ClN3O4S
Target:
HDAC|||Reactive Oxygen Species|||Apoptosis
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