Icerguastat (Sephin1) Carbonate, a Guanabenz derivative lacking alpha2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). It inhibits the dephosphorylation of eIF2alpha, thereby prolonging the protective response. Additionally, Icerguastat Carbonate exhibits antiprion activity.
Molecular Weight:
258.66
CAS Number:
[1883549-35-6]
Formula:
C9H11ClN4O3
Target:
Phosphatase
T208657
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