Topoisomerase I inhibitor 14 (Compound 4h) acts as an inhibitor of topoisomerase I. It suppresses the proliferation of A549 and C6 cells, with IC50 values of 4.56 µM and 13.17 µM, respectively. The compound shows no significant toxicity towards healthy NIH3T3 cells (IC50 of 74.44 µM) and demonstrates anticancer activity.
Formula:
C28H29N9O2S
Target:
Topoisomerase
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