BET-IN-21 (compound 16) is a BET (Bromo and Extra-Terminal domain) inhibitor capable of penetrating the blood-brain barrier, with a Ki value of 230 nM. It suppresses microglial activation and demonstrates therapeutic effects in mice with experimental autoimmune encephalomyelitis.
Molecular Weight:
344.41
CAS Number:
[3014815-06-3]
Formula:
C20H20N6
Target:
Epigenetic Reader Domain
T208765
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