Anti-inflammatory agent 74 (B5) is known for its ability to inhibit NO, IL-6, and TNF-alpha, with IC50 values of 10.88 µM and 4.93 µM for NO and IL-6, respectively. It alleviates acute lung injury (ALI) by modulating inflammatory mediators and inhibiting the MAPK and NF-kappaB signaling pathways.
Formula:
C41H51NO14
Target:
TNF|||Interleukin|||p38 MAPK|||NF-kappaB
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