(+)-JQ1-OH is the primary metabolite of (+)-JQ1. (+)-JQ-1 (JQ1) is a potent, specific, and reversible inhibitor of BET bromodomain, with IC50 values of 77 nM for the first bromodomain and 33 nM for the second bromodomain (BRD4(1/2)). Additionally, (+)-JQ-1 stimulates autophagy (autophagy).
Formula:
C23H25ClN4O3S
Target:
Drug Metabolite
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