Aromatase-IN-3 (compound 7d) is an aromatase inhibitor with an IC50 of 54 nM. It effectively suppresses the conversion of androstenedione to estrogen catalyzed by aromatase, demonstrating significant tumor growth inhibition in breast cancer cell lines, suggesting its potential application in ER+ cancer research.
Formula:
C38H38N2O3
Target:
Cytochromes P450
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