PRMT5-IN-33 (compound A8) is a selective inhibitor of PRMT5 that competes with SAM, exhibiting an IC50 of 10.9 nM. It induces apoptosis and inhibits the proliferation of Z-138 and MOLM-13 cells, demonstrating antitumor activity.
Formula:
C25H24BrN5O3S
Target:
Apoptosis|||Histone Methyltransferase
* VAT and and shipping costs not included. Errors and price changes excepted
