B-Raf IN 17 (Compound 8e) is an effective, orally active type II multi-kinase inhibitor. It shows potent cellular inhibition against BRAFWT, VEGFR-2, and FGFR-1 in the A375 cell line, with IC50 values of 0.02, 0.18, and 1.65 µM, respectively. B-Raf IN 17 is applicable for cancer research.
Formula:
C22H14BrN5O2
Target:
Raf|||FGFR|||VEGFR
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