NAE-IN-1 (compound X-10) is a potent inhibitor of NAE1. It induces apoptosis and causes cell cycle arrest in the G2/M phase. Furthermore, NAE-IN-1 increases ROS levels and inhibits cell migration, demonstrating antiproliferative activity.
Formula:
C29H30N4O2S
Target:
Reactive Oxygen Species|||NEDD8|||Apoptosis
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