HGPRT/TBrHGPRT1-IN-1 (Compound 5) is a selective inhibitor of human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and Trypanosoma brucei TBrHGPRT1, with a Ki of 3 nM. By inhibiting HGPRT/TBrHGPRT1, it ultimately reduces cell growth. HGPRT/TBrHGPRT1-IN-1 is primarily used in research on infectious diseases and cancer.
Formula:
C15H24N6O9P2
Target:
Parasite
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