TEAD-IN-9 (compound 17) is a TEAD1 inhibitor with an IC50 of 0.29 µM. It targets the palmitoyl pocket of TEAD, effectively inhibiting the binding of YAP-TEAD and blocking the transcriptional function of YAP-TEAD.
Formula:
C23H23F3N3O3P
Target:
YAP
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