XYD190 (Compound 14g) is an orally active degrader of CBP/p300. It inhibits the bromodomain of CBP/p300 with an IC50 of 483.7 nM and demonstrates antitumor activity against acute myeloid leukemia.
Formula:
C55H50F2N10O7
Target:
PROTACs|||Epigenetic Reader Domain
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