SIRT-IN-4 is an inhibitor specifically targeting the NAD+-dependent lysine deacetylase Sirtuin2 (Sirt2) with an IC50 of 0.35 µM. It effectively inhibits Sirt2 deacetylation, thereby reducing cell viability and impeding the migration of prostate cancer cells. SIRT-IN-4 is useful for research on Sirt2s roles in cell cycle regulation and gene expression control.
Formula:
C29H28ClFN4O2
Target:
Sirtuin
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