LC-MI-3 is an orally active and potent PROTAC degrader of interleukin-1 receptor-associated kinase 4 (IRAK4), with a DC50 value of 47.3 nM. It effectively inhibits the activation of downstream NF-kappaB signaling. LC-MI-3 is applicable for research in both acute and chronic inflammatory skin conditions.
Formula:
C39H36N8O8
Target:
PROTACs|||IRAK|||NF-kappaB
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