PARL-IN-1 TFA is a potent PARL inhibitor with an IC50 value of 28 nM. It inhibits PARL, leading to significant activation of the PINK1/Parkin pathway. Additionally, PARL-IN-1 TFA enhances PINK1/Parkin-dependent mitophagy.
Formula:
C41H57F3N6O9
Target:
Mitophagy|||PTEN
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