Hdm2 E3 ligase inhibitor 1, CAS [[414905-09-2]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T210014
Supplier Catalog Number:
T210014
Alternative Catalog Number:
TGM-T210014-10MG,TGM-T210014-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Hdm2 E3ligaseinhibitor 1 (Compound 1) is a reversible inhibitor of Hdm2-mediated p53 protein ubiquitination, with an IC50 of 12.7 µM. It binds to Hdm2, blocking the transfer of ubiquitin catalyzed by Hdm2 from pre-linked Ub-Ubc4 to p53, thereby inhibiting p53 ubiquitination, stabilizing p53 protein in tumor cells, and exerting antitumor activity.
Molecular Weight:
350.24
CAS Number:
[414905-09-2]
Formula:
C10H8F6N2O3S
Target:
MDM-2/p53|||E1/E2/E3 Enzyme
T210014
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