HPK1-IN-48 (compound 14g) is a potent inhibitor of hematopoietic progenitor kinase 1 (HPK1), with an IC50 value of 0.15 nM. Additionally, HPK1-IN-48 significantly inhibits the phosphorylation of SLP76, demonstrating an IC50 of 27.92 nM.
Formula:
C33H38N8O3
Target:
MAPK
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