PMEG-DP disodium is an effective inhibitor of DNA polymerase (IC50=2.5 µM), exerting strong inhibitory effects particularly on DNA polymerases alpha and delta. As the active metabolite of GS-9191, it efficiently impedes the growth of cell lines infected with human papillomavirus (HPV). PMEG-DP disodium is useful in research related to HPV-associated diseases.
Formula:
C8H12N5Na2O11P3
Target:
DNA/RNA Synthesis
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