BRD4-BD1/2-IN-3 is a highly selective BRD4 BD2 inhibitor (IC50 = 0.41 nM) that exhibits strong selectivity over BRD4 BD1 and potently suppresses LPS-induced IL-6 expression. BRD4-BD1/2-IN-3 modulates TNF and NF-kappaB signaling pathways, providing a valuable tool for studying BRD4 biology and for researches on inflammatory diseases.
Molecular Weight:
362.39
Purity:
99.63%
CAS Number:
[3106588-54-6]
Formula:
C20H18N4O3
Target:
Epigenetic Reader Domain|||Others
T210452
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