BMS-986470 is a CRBN E3 ubiquitin ligase modulator (CELMoD) that activates fetal hemoglobin (HbF). It is an orally available molecular glue degradator targeting ZBTB7A and WIZ protein degradation, thereby inducing gamma globin synthesis and activating HbF. It is applicable for studying sickle cell disease (SCD).
Molecular Weight:
523.54
CAS Number:
[3036554-12-5]
Formula:
C29H25N5O5
Target:
Molecular Glues|||PROTACs
T210489
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