MOMA-341 is a selective, ATP-competitive WRN allosteric inhibitor that binds to the cysteine 727 site of WRN. It induces DNA damage, cell death, and tumor regression in dMMR/MSI-H mouse models and can be used to study advanced and metastatic solid tumors.
Molecular Weight:
570.54
CAS Number:
[3078276-74-8]
Formula:
C28H26F4N6O3
Target:
DNA/RNA Synthesis
T210496
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