Simepdekinra (Compound 221) is a potent IL-17A modulator with IC50 values 10 nM for IL-17A/A HEK-Blue cells and 10-100 nM for IL-17A/F HEK-Blue cells, suitable for studying psoriasis, ankylosing spondylitis, and psoriatic arthritis.
Molecular Weight:
667.81
CAS Number:
[2978700-29-5]
Formula:
C35H50FN7O5
Target:
IL Receptor
T210537
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