A2AR modulator-1, CAS [[3007566-23-3]] Preis auf Anfrage

Catalog Number: TGM-T210624
Article Name: A2AR modulator-1, CAS [[3007566-23-3]] Preis auf Anfrage
Biozol Catalog Number: TGM-T210624
Supplier Catalog Number: T210624
Alternative Catalog Number: TGM-T210624-10MG,TGM-T210624-50MG
Manufacturer: TargetMol
Category: Biochemikalien
A2AR modulator-1 (Compound 45) is a selective negative allosteric modulator of the adenosine A2a receptor (A2aR), with an IC50 value of 9 nM. It reduces the affinity of endogenous adenosine for the receptor and inhibits the activation of the cAMP signaling pathway. A2AR modulator-1 effectively restores pCREB phosphorylation in CD4+ T cells, reverses immunosuppression in the tumor microenvironment, and shows potential in inhibiting tumor growth and metastasis in a triple-negative breast cancer model.
Molecular Weight: 380.45
CAS Number: [3007566-23-3]
Formula: C23H20N6
Target: Adenosine Receptor
T210624