A2AR modulator-1, CAS [[3007566-23-3]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T210624
Supplier Catalog Number:
T210624
Alternative Catalog Number:
TGM-T210624-10MG,TGM-T210624-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
A2AR modulator-1 (Compound 45) is a selective negative allosteric modulator of the adenosine A2a receptor (A2aR), with an IC50 value of 9 nM. It reduces the affinity of endogenous adenosine for the receptor and inhibits the activation of the cAMP signaling pathway. A2AR modulator-1 effectively restores pCREB phosphorylation in CD4+ T cells, reverses immunosuppression in the tumor microenvironment, and shows potential in inhibiting tumor growth and metastasis in a triple-negative breast cancer model.
Molecular Weight:
380.45
CAS Number:
[3007566-23-3]
Formula:
C23H20N6
Target:
Adenosine Receptor
T210624
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