SK2188 is a potent and selective PROTAC degrader targeting AURKA (DC50 = 3.9 nM). It induces DNA damage and apoptosis (Apoptosis), indirectly degrades MYCN, and inhibits tumor cell proliferation, offering insights for research on MYCN-amplified neuroblastoma.
Molecular Weight:
893.38
CAS Number:
[3038446-94-2]
Formula:
C43H46ClFN6O10S
Target:
Caspase|||Aurora Kinase|||Apoptosis|||PROTACs
T210633
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