PROTACHBeAg degrader-1 is a PROTAC-based targeted degrader of HBeAg. It effectively recruits the VHL E3 ligase, yet its ability to degrade the hepatitis B virus protein (HBeAg) does not depend on VHL recruitment. This compound decreases levels of both secreted and intracellular HBeAg and is suitable for research involving the hepatitis B virus (HBV).
Target:
PROTACs|||HBV
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