THR-beta agonist 9, CAS [[2920045-74-3]] Preis auf Anfrage

Product Overview

• Article Name: THR-beta agonist 9, CAS [[2920045-74-3]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T210706
• Supplier Catalog Number: T210706
• Alternative Catalog Number: TGM-T210706-10MG,TGM-T210706-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

THR-beta agonist 9 is a potent and selective THR-beta activator, which shows sensitivity to His435 mutations with an EC50 of 3.2 nM. It demonstrates moderate selectivity, approximately 10-fold, and effectively activates various His435 mutants (H435A, H435Y, and H435R), with EC50 values ranging from 134.2 nM to 515.5 nM. THR-beta agonist 9 presents potential for research into conditions such as dyslipidemia, metabolic syndrome-associated steatohepatitis (MASH), and resistance to thyroid hormone (RTH).

Product Properties

• Molecular Weight: 418.4
• CAS Number: [2920045-74-3]
• Formula: C23H18N2O6
• Target: Acetyl-CoA Carboxylase|||AMPK|||Thyroid hormone receptor(THR)|||Mitochondrial Metabolism

Images

T210706