Hsp90-Cdc37-IN-4, CAS [[2758818-41-4]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T210708
Supplier Catalog Number:
T210708
Alternative Catalog Number:
TGM-T210708-10MG,TGM-T210708-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Hsp90-Cdc37-IN-4 is a novel derivative of triptolide that inhibits the protein-protein interaction (PPI) between Hsp90 and Cdc37. It selectively inhibits casein kinase 2 (CK 2), reducing the phosphorylation of its substrate Cdc37 at the serine 13 site. Additionally, Hsp90-Cdc37-IN-4 induces cell cycle arrest in the G0/G1 phase and triggers apoptosis via the mitochondrial pathway. This compound exhibits significant anti-breast cancer activity.
Molecular Weight:
638.84
CAS Number:
[2758818-41-4]
Formula:
C40H50N2O5
Target:
HSP|||Apoptosis|||Casein Kinase
T210708
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