PARG-IN-6 (Compound 2) is an orally bioavailable PARG inhibitor with an IC50 of 0.3 nM. It exhibits significant anticancer activity against cancer cells, with an IC50 of 0.0368 µM for HCC1395 cells. PARG-IN-6 shows potential for research in colon cancer, appendiceal cancer, and pancreatic cancer.
Molecular Weight:
647.69
CAS Number:
[3083070-66-7]
Formula:
C24H25F4N7O4S3
Target:
Poly(ADP-ribose) Glycohydrolase (PARG)
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