VU0514009 is a competitive antagonist of chemokine-like receptor 1 (CMKLR1) with an EC50 of 2 nM. It effectively inhibits chemerin-9-induced arrestin recruitment and receptor internalization, significantly reducing Ca2+ flux responses in HEK293 cells. This compound shows potential for research in inflammatory diseases and metabolic syndrome.
Molecular Weight:
493.98
CAS Number:
[932973-77-8]
Formula:
C21H20ClN3O5S2
Target:
Chemerin Receptor
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