PROTACHPK1 Degrader-4 (compound E3) is an orally active, selective PROTACHPK1 degrader with a DC50 of 3.16 nM. It exhibits over 1000 times greater selectivity for PROTACHPK1 compared to GLK. PROTACHPK1 Degrader-4 enhances immune activation and is useful in research for colon cancer and lymphoma.
Target:
MAPK|||PROTACs
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